diff --git a/gdb/testsuite/ChangeLog b/gdb/testsuite/ChangeLog
index bc6b126c1b2..4a6d48e2af7 100644
--- a/gdb/testsuite/ChangeLog
+++ b/gdb/testsuite/ChangeLog
@@ -1,3 +1,7 @@
+2020-12-21  Markus Metzger  <markus.t.metzger@intel.com>
+
+	* gdb.btrace/multi-inferior.exp: Skip if use_gdb_stub.
+
 2020-12-21  Markus Metzger  <markus.t.metzger@intel.com>
 
 	* gdb.python/py-record-btrace.exp: Make test names unique.
diff --git a/gdb/testsuite/gdb.btrace/multi-inferior.exp b/gdb/testsuite/gdb.btrace/multi-inferior.exp
index 23bc852c565..cfccc581681 100644
--- a/gdb/testsuite/gdb.btrace/multi-inferior.exp
+++ b/gdb/testsuite/gdb.btrace/multi-inferior.exp
@@ -27,6 +27,11 @@ if { [skip_btrace_tests] } {
     return -1
 }
 
+if { [use_gdb_stub] } {
+    unsupported "test creates multiple inferiors"
+    return -1
+}
+
 standard_testfile
 if [prepare_for_testing "failed to prepare" $testfile {} {debug}] {
     return -1